Experimental Evaluation of the Effectiveness and Safety of a New Propandic Acid Derivative Exhibiting Cardiotropic Action
نویسندگان
چکیده
An entire cycle of preclinical studies 4-[(3-ethoxy-3-oxopropanoyl)amino]benzoic acid (etmaben) exhibiting cardiotropic action was carried out. Its potential mechanism and pharmacological effects, general toxic effects in acute chronic experiments, specific types toxicity (allergenicity, immunotoxicity, reproductive toxicity, mutagenicity), pharmacokinetics were studied. The drug found to have a pronounced effect positive safety profile, which justifies the launch phase I clinical trials.
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ژورنال
عنوان ژورنال: Biomedicina
سال: 2022
ISSN: ['2386-6942']
DOI: https://doi.org/10.33647/2074-5982-18-3-109-112